1

Welcome and role call

BGO, all

2

 Allergy/hypersensitivity editorial guidelines

BGO

• Update on allergy/hypersensitivity model and allergy to x revision project

• Input from Allergy-hypersensitivity clinical reference group

  • The term "pseudoallergy" is obsolete as discrete pathophysiologic mechanisms have been identified. Recommendation is to replace with non-allergic hypersensitivity which will align more closely with WAO/EAAAI nomencalture

• Yongsheng Gao and Former user (Deleted) met 8/23/2017 to discuss how to prioritize content revision for Jan. 2018 release.

• Yongsheng Gao will produce draft document and will finalize with Bruce Goldberg and Former user (Deleted)

3

Arthritis syndromes

BGO

• Certain arthritis conditions can be represented as a joint inflammation as well as a systemic/multisystem disorder.

4

Modeling fetal and maternal related concepts

PBR

• Alternate model using occurrence role

5

During and/or after attribute

BGO

• Motion to inactivate During and/or after (attribute)

Rationale:

The default temporal context of a disorder caused by a procedure is that the disorder must occur either during, after or both during and after the procedure and is thus implied if a temporal relationship between a disorder and a procedure is not clearly stated in the fully specified name or otherwise understood from the definition of the concept. In such cases, no temporal relationship needs to be added to the definition of the concept. I have clarified this point in the document. Before, during and/or after i.e. temporally related to is retained primarily to define the perioperative state.

6

Sepsis/organ dysfunction syndrome

YGA, BGO

• There are 43 subconcepts under 238151006|Sepsis-associated organ dysfunction (disorder)|. They need to be reviewed and revised following the Editorial Guide on X with Y associations. Some specific issues need to be addressed:

1. Which pattern should this concept and its subconcepts belong to, e.g. due to vs. co-occurrent and due to?

2. Should these be implemented as description changes of FSNs or inactivation of concepts?

3. Should 238151006|Sepsis-associated organ dysfunction (disorder)| be subconcept of 91302008|Sepsis (disorder)|?

4. Should 91302008|Sepsis (disorder)| is a subconcept of 238149007|Systemic inflammatory response syndrome (disorder)|?

5. Should sepsis is a subconcept of 238147009|Organ dysfunction syndrome (disorder)|?

6. Should 76571007|Septic shock (disorder)| is a subconcept of sepsis?

ngoing discussion has raised the following points:

1. Organ dysfunction can persist after infection resolves, therefore not necessarily co-occurrent and thus co-occurrent and due to modelling pattern may not be appropriate.

2. Should sepsis be considered a kind of infectious disease? If so then another model would utilize pathological process infectious process to capture infectious disease as an additional parent.

3. Is a pathological process of infectious process correct for sepsis or is dysregulated host response a better pathological process to define sepsis?

7

AOB, adjourn

ALL

• Additional agenda topics for October business meeting

• Next meeting likely to be held after the October business meeting