1

Welcome and role call

Bruce Goldberg

2

Device complications

Bruce Goldberg

Daniel Karlsson

Discussion of proposed model for equipment/device problems with regard to equipment/device observables

• Daniel Karlsson unable to attend call.

  • Discussion tabled for a future call

• Former user (Deleted) to supply EU definitions of equipment and device. Bruce Goldberg to examine how these may differ from WHO definitions

https://ec.europa.eu/growth/sectors/medical-devices/regulatory-framework_en

• Above link does not contain definitions

• Former user (Deleted) will attempt to locate a document that does contain the EU definitions of device and equipment

3

Pathological process vs. pathogenesis

Jim Case

Bruce Goldberg

• Review and revision of the editorial guidance for use of PATHOLOGICAL PROCESS and the associated qualifier value set.

• Coordinate with Event-condition-episode changes (Structure-disposition-process proposal), and coordinate with ASSOCIATED-MORPHOLOGY modeling.

• Jim Case not on call.

  • Discussion tabled for ECE face to face meeting in London

4

Allergies

Bruce Goldberg

• Use of GCIs for modeling allergic condition class (SDP)

• Revised briefing document with timeline

• Modeling of allergy to combined drugs discussed. Using GCIs results in allergy to each component being subsumed by allergy to the combined drug which seems more beneficial than the current state where allergy to the combined drug is subsumed by allergy to both components. Further discussion needed to determine whether the former situation is correct.

  • Discussion from March 8 Allergy CRG call

    • Some concern that with revised model an allergy to e.g. amoxicillin + clavulanic acid would not trigger an alert in someone allergic to amoxicillin

    • Further discussion to take place during Allergy CRG face to face meeting in London

• Former user (Deleted) clarified current work involving retirement of allergy to inappropriate groupers be made known by implemeters involved in decision support.

  • Release notes would be acceptable

  • Release notes prepared by Former user (Deleted)

Out of scope |Allergy to X (disorder)| concepts, as identified by the Allergy/Hypersensitivity and Intolerance Clinical Reference Group, have been inactivated. See the CRG Confluence space for additional details.

Allergies/Hypersensitivity and Intolerance Clinical Reference Group

A list of the concepts reviewed and action taken is updated periodically and is located at:

Allergic Disposition Review

5

Simple co-occurrence editorial guidelines

Bruce Goldberg

Jim Case

Revised editorial guidelines for combined disorders

• Reviewed by group and approved

6

Device infections

Bruce Goldberg

Jim Case

Draft editorial guidelines

Awaiting approval by Jim Case

Yongsheng Gao suggested a more appropriate finding site for prosthetic joint infection would be joint region structure (would need to be created) rather than joint structure.

• Guidelines revised

Note that above approach may not be generalizable to other device infections e.g. 240272004 |Bone fixation device infection (disorder)| which inherits a parent of Infection of bone (disorder) in spite of the descendants of 240272004 being external fixation infections. Requires further discussion.

7

Sepsis model

Bruce Goldberg

Jim Case

Addition of pathological process dysregulated host response (a child of abnormal immune response) in test model results in sepsis inferring a parent of Disorder of immune function. Group felt this was OK.

Still Need approval by Jim Case

8

Face to face meeting - London

Bruce Goldberg

1/2 day meeting Monday, April 9th 13:30-17:00

• Call for topics

Possible topics:

Domain specific guidelines

1. HIV complications

Device complications ?

Pathological process vs. pathogenesis

9

AOB, adjourn

ALL