1

Welcome and role call

@Bruce Goldberg

2

Device complications

@Bruce Goldberg

@Daniel Karlsson

Discussion of proposed model for equipment/device problems with regard to equipment/device observables

• Device complications.pptx

• @Former user (Deleted) to supply EU definitions of equipment and device. @Bruce Goldberg to examine how these may differ from WHO definitions

https://ec.europa.eu/growth/sectors/medical-devices/regulatory-framework_en

Device complications additional examples.xlsx

3

Pathological process vs. pathogenesis

@Jim Case

@Bruce Goldberg

• Review and revision of the editorial guidance for use of PATHOLOGICAL PROCESS and the associated qualifier value set.

• Coordinate with Event-condition-episode changes (Structure-disposition-process proposal), and coordinate with ASSOCIATED-MORPHOLOGY modeling.

• Content development fast track artf221697-PATHOLOGIC PROCESS.docx

4

Allergies

@Bruce Goldberg

• Use of GCIs for modeling allergic condition class (SDP)

  • Allergy model updates.pptx

• Revised briefing document with timeline

  • Allergy remodel briefing document with workflow.docx

• Modeling of allergy to combined drugs discussed. Using GCIs results in allergy to each component being subsumed by allergy to the combined drug which seems more beneficial than the current state where allergy to the combined drug is subsumed by allergy to both components. Further discussion needed to determine whether the former situation is correct.

  • Will bring to allergy CRG

• @Former user (Deleted) suggested current work involving retirement of allergy to inappropriate groupers be reviewed by implemeters involved in decision support.

  • Above not practical.

  • Release notes prepared by @Former user (Deleted)

Out of scope |Allergy to X (disorder)| concepts, as identified by the Allergy/Hypersensitivity and Intolerance Clinical Reference Group, have been inactivated. See the CRG Confluence space for additional details.

Allergies/Hypersensitivity and Intolerance Clinical Reference Group

A list of the concepts reviewed and action taken is updated periodically and is located at:

Allergic Disposition Review

Simple co-occurrence editorial guidelines

@Bruce Goldberg

@Jim Case

Revised editorial guidelines for combined disorders

Simple co-occurrence.docx

5

Device infections

@Bruce Goldberg

@Jim Case

Draft editorial guidelines

Editorial guidelines approved by group

Device infections.docx

• Awaiting approval by @Jim Case

6

Sepsis model

@Bruce Goldberg

@Jim Case

Addition of pathological process dysregulated host response (a child of abnormal immune response) in test model results in sepsis inferring a parent of Disorder of immune function. Group felt this was OK.

• Need approval by @Jim Case

Sepsis – test modeling with pathological process.pptx

6

Face to face meeting - London

@Bruce Goldberg

1/2 day meeting Monday, April 9th 13:30-17:00

• Call for topics

7

AOB, adjourn

ALL