2021-11-15 - Cancer Synoptic Reporting Project Group Meeting

1

Status of initial sub

@Scott Campbell

• Confirm date of 2021-10-31 availability

2

Intactness/quality of specimen concepts

@Scott Campbell

1. Discuss representation of "intactness" and specimen quality (colon, ovary, thyroid)
   
   
   

2. Confirm Business Meeting Conclusion

Approach agreed upon.  Create new concept |Anatomic integrity (property)|.  When used with |Inheres in| = some (specimen), then the discussion is about the anatomic integrity of the specimen which is appropriate for CSRWG observations.

When used with |Inheres in| = some (body structure), the discussion is about the anatomic integrity of the body structure as is the case discussed pertaining to in vivo observations.

Not discussed

3

IHC

@Scott Campbell

Discuss model, adjust as necessary, inclusion of related gene?

1. Generic model for presence of protein by IHC discussed and tentatively agreed upon.  COMPONENT = <<SUBSTANCE
   
   No relationship to gene necessary here.
   
   
   

2. @Scott Campbellto generate model for review with examples.  How/if to represent nuclear, membraneous, cytoplasmic protein

3. @Scott Campbell to expand on generic molecular and cytogenetic model