2021-10-20 - Cancer Synoptic Reporting Project Group Meeting - SNOMED International Business Meeting

1

Status of initial sub

@Scott Campbell

• Confirmation on concepts published (~350 new concepts in 31-10-2021 release!)

• Great progress!  (It was only 14 months ago, or so, that this project group really started to publish!!!)

2

Intactness/quality of specimen concepts

@Scott Campbell

1. Discuss representation of "intactness" and specimen quality (colon, ovary, thyroid)

More to discuss, but mirriam-webster definition helps: : the quality or state of being complete or undivided : COMPLETENESS

Perhaps two properties.  

Ovary (anatomic integrity) inheres in excised ovary 

Mesorectum (completeness of excision/quality of excision) inheres in excised mesorectum specimen

Suggest: Use of |Property| = |anatomic integrity (property)| for both and |Inheres in| the specimen for path

|Inheres in |= body structure for trauma, radiology, etc. 

Approach agreed upon.  Create new concept |Anatomic integrity (property)|.  When used with |Inheres in| = some (specimen), then the discussion is about the anatomic integrity of the specimen which is appropriate for CSRWG observations.

When used with |Inheres in| = some (body structure), the discussion is about the anatomic integrity of the body structure as is the case discussed pertaining to in vivo observations.

3

Tumor Deposit

@Scott Campbell

Review model for colon and appendix

Discuss with # of Tumor Deposits

Did not discuss

4

Microsatellites/tumor nodules

@Scott Campbell

Melanoma

Did not discuss

5

Mitotic rate

@Scott Campbell

Multiple protocols

number cell in Cell division phase phase/total count of cells in a normalized area

6

Metastasis observable

@Scott Campbell

Inclusion of primary tumor site in observable as |Inherent location| in metastatic spread observables

OK to proceed.

7

Tumor descriptions

@Scott Campbell

Tumor description (adrenal); Rhabdoid; Sarcomatoid (kidney); histologic patterns (lung)

Did not discuss

8

Lymph node locations/stations

@Scott Campbell

Discuss approach to lymph node body structures and differences in naming/locations (example AJCC esophageal cancer vs. JES esophageal cancer)

Did not discuss

9

IHC

@Scott Campbell

Model review and discussion

ER, PR, Her2, Ki-67, PD-L1, MLH1, PMS2, MSH2, MSH6,ATRX expression, Beta-catenin expression, reticulin

How are these broken out/logically organized?  Nuclear proteins? Cytoplasmic: Receptors?

Did not discuss

10

Communication to users

@Scott Campbell

Strategies to communicate work products?

Did not discuss

11

Tumor Staging

@Daniel Karlsson @Scott Campbell

Discussed use of TNM-category levels....

AJCC wants SI to eliminate all  TNM content from terminology.

UICC may be an alternative.

@Daniel Karlsson to discuss at member forum next week (26-10-2021)

What are use cases?  

CDSS, research, electronic data exchange between systems...