LOINC Components: Age and Gestational age

Summary of discussions in OIMP call, August 2017 (To be continued in the next OIMP call):

Two models to consider:

1) Age as "property" (Quantity observable)

2) Age as "process duration" (Process observable, characterizes life process)

Swapna noted that there other LOINC terms that contain age as "age at". We need to consider them as well:

Also consider the following:

OIMP meeting in Bratislava:

Reviewed the two modelling options with examples of use of additional attribute-values:

• Quality observable with age as property

| Observable | :
| Property | = | New | Age |,
| Inheres in | = | Patient | / | Human being | OR | Human oocyte donor (person) | OR | Specimen |,
| Precondition | = | New | At time of diagnosis |,
| Techniques | = | Calculation Technique|

• Process Observable with property = Duration

| Observable | :
| Property | = | New | Duration |,
| Characterizes | = | Life |, |Gestation/Development|, |Sample degradation|

| Inheres In (similar attribute?) = | Patient | / | Human being | OR | Human oocyte donor (person) | OR | Specimen |,

| Precondition = | New | At time of diagnosis|

| Techniques | = | Calculation Technique|

Examples in SNOMED and LOINC:

• Age in patient:

• • 424144002 | Current chronological age (observable entity) |

  • 30525-0 | Age (Age:Time:Pt:^Patient:Qn)

• Age in someone other than patient:

• • 443443002 | Age of carer (observable entity) |

  • 68327-6 | Egg donor age (Age:Time:Pt:^Egg donor:Qn )

• Age of fetus:

• • 57036006 | Fetal gestational age (observable entity) |

  • 18185-9 | Gestational age (Gestational age:Time:Pt:^Fetus:Qn)

• Age of something:

• • 167816006 | Semen sample age (observable entity) |

  • 49546-5 | Age of Blood specimen (Specimen age:Time:Pt:Bld:Qn)

• Age at X (X is a precondition):

• • 412726003 | Length of gestation at birth (observable entity) |

  • 445872007 | Length of gestation at time of procedure (observable entity) |

  • 63932-8 | Age at diagnosis (Age at diagnosis:Time:Pt:^Patient:Qn)

• Age by Y technique: e.g

• • 123980006 | Bone age (observable entity):

  • 29553-5 | Age calculated (Age:Time:Pt:^Patient:Qn:Calculated)

• Age at X (precondition) by Y (technique)

• • 444135009 | Estimated fetal gestational age at delivery (observable entity) |

• Discussions:

  • Use Process Observable model for age ( as well as duration). 

    • Ease of modeling uses cases like gestational age, neonatal age, chronological age and easier to express change from gestation to life

    • Expand the range of characterizes to include Procedures)

  • Add Inheres In = Patient when the attribute/value applies.

  • Fetal age characterizes gestation process and starts from conception up to and terminated by birth. Inheres in Fetal structure. Neonatal age is Age immediately after birth/delivery and characterizes life, which inheres In the patient (baby).

  • Change "sample degradation process" to "sample aging process"

  • Add definitions to the added processes (e.g. gestation process)

  • Chronological is required in the Chronological age to differentiate it from Biological age, bone age, etc.

  • Deprecate existing concept “105727008 | Age AND/OR growth period (observable entity) |

• Remaining item:
  
  
  

  • What is the difference if any between "At time of birth" and "at time of delivery".

  • Is a precondition required for existing concept “424144002 | Current chronological age (observable entity) |". Should we remove description "age" from this concept and add it to New | Chronological age | 
    
    

  • The range for Inheres In needs to change to include descendants of 125676002 | Person (person)?

  • Does the same extension applies to 14679004 | Occupation (occupation) | → e.g. Carer in “Age of carer”

    
    
    

Action Item:

• Farzaneh Ashrafi and Suzanne Santamaria: Submit a request for MRCM change: Expand the range of characterizes to include Procedures
  
  

• Daniel Karlsson: Update Inception / Elaboration document to consider the above noted change