Today's meeting
Further thoughts on today's discussion topics
Comments
For modeling secondary disorders, it became apparent that it is almost not possible to fully define the grouper concept by a single definition. The key problem for the manual assignments is unreliability that often missing subtypes.
We can employ the GCI (General Concept Inclusion) to achieve the intended DL classification results. This approach can avoid manual assignment of subtypes for secondary disorders. For example, Secondary diabetes (disorder) is can be defined as following:
Secondary diabetes SubClassOf Diabetes
Diabetes and (associated with some Disorder) SubClassOf Secondary diabetes
Diabetes and (causative agent some Drug) SubClassOf Secondary diabetes
Diabetes and (associated with Procedure) SubClassOf Secondary diabetes
The definition will automatically classify the disorders, drug induced diabetes, posttransplant diabetes, diabetes due to pancreatic disease etc. under the secondary diabetes.
This is a good business case that we need to move forward to OWL and utilise the advanced features in OWL EL.
Thanks Yong. This would be an elegant solution that hopefully can be implemented in the not too distant future. I should also point out that specific disorders may be secondary to not only other disorders, procedures and drugs but also other substances, physical objects, physical forces and perhaps events. A complete list of possible associations will need to be compiled for each secondary disorder.
Bruce
Thanks Bruce, indeed, most secondary disorders can share the similar definition but some could require specific ranges. We need to test the solution and propose possible modeling patterns.
Hi all. When I strated writing up the minutes of today's meeting I had the following concerns about some of the decisions we made:
A proposal was discussed for modeling secondary disorders as disorder X associated with disease (disorder). Secondary disorders are generally used as groupers for disorder complications modeled using more specific associations such as due to, after and caused by and thus associated with would be permissible in this context. This approach however will fail to autoclassify disorders secondary to material objects, procedures, events, etc. Currently, disorders related to material agents are manually asserted under (primitive) secondary disorders. Disorders related to other disorders are modeled and fully defined as disorder X associated with disease.
Possible approaches:
Continue present practice of keeping Secondary X (disorder) primitive and manually asserting subtypes
Reire Secondary X (disorder) as ambiguous. Retain Disorder X associated with another disease and disorders secondary to other than diseases such as Drug related disorder both of which are fully defined
Other?
Recommendation made to move all unspecified drug overdoses to event hierarchy and rename specified overdose disorders as Injury due to X overdose (disorder). Further discussion required re. overdose finding as an abnormal (elevation) of a drug on a laboratory test as finding may not be due to an overdose but rather to a metabolic abnormality.