2024-07-22 - Cancer Synoptic Reporting Project Group Meeting

1

Updates:

a. UICC

b. ICCR

@Scott Campbell 

1. UICC in process

2. ICCR in process

2

Implementation Guide Update

@Scott Campbell

1. Ready to go with some minor updates

3

ICCR Terminology Bindings 

@Scott Campbell 

1. Will use NLM SDC/FHIR construct for content management and distribution

4

Manuscript update

@Scott Campbell 

1. Comments back by 6/15.

5

Clinical findings resolution

@Scott Campbell

@Scott Campbell reviewing with editors

6

Immunostains

@Scott Campbell 

Discussion on how to proceed

1.  How to encode the data "on the slide"?

2. Is this a series of independent observable entities that collectively tell the "story"?  (Similar to the intent of the synoptic?)

For example:

1. Gene/protein target of stain

2. Antibody used (and clone)

3. Cytoplasma?  Membraneous?  Nuclear?

4. Distribution

Need to define the building blocks (legos) of the data on the slide.  How the legos can be put together would need to be defined.  And how much detail do the legos need to be defined.

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PDL1 to start

1. Measuring - Positivity of presence of ant and semi-quantitative

2. How measuring

3. antibody used and clone

1. Maybe precoord not best for now.

2. Set of bound data points (observations?)

3. Try a couple of options/example

1 hour

1. BN on Histology Quality overview

2. BN on Obs. ent vs. Clinical findings
   
   
   

3. Direct local extension BN.