2018-07-16 - OBSERVABLE Meeting

1

Welcome & apologies

@Daniel Karlsson

2

Conflicts of interest

@Daniel Karlsson

• None stated

3

Previous minutes

@Daniel Karlsson

4

Free and Total Substances

@Daniel Karlsson

@Former user (Deleted)

@Yongsheng Gao

@Farzaneh Ashrafi

• See item discussion page.

• The current plan is to represent the base substance, the bound and the free substance as three siblings with a "substance X and derivatives" common subsumer.

• This would support the Observables use cases of allowing querying for substances without regard for "bound-ness", and to distinguish between bound, free, and total.

• Three patterns for Observables would be:

  • Free X Observable === Observable & component = Free X

  • Bound X Observable === Observable & component = Bound X (or X bound to Y)

  • Total X Observable === Observable & component X (base substance concept)

5

Susceptibility

@Suzanne Santamaria

@Farzaneh Ashrafi

• Mapping of LOINC component for Susceptibility LOINC terms

• There will likely be a new "diagnostic product" hierarchy parallel to the medicinal product hierarchy, reusing attributes and patterns from that hierarchy. The priority of this work is currently unknown

  • The new category would need modeling guidance (cf. Clinical Drug (CD) Concept - Pattern 1a, permission needed!). Some of the items that should be considered are as follows (from Farzaneh and Toni):

  • Do we need a new semantic tag?

  • Can the concepts be modelled with a single pattern/template or are there multiple patterns/templates needed?

  • Can we reuse of some of attributes in medicinal product and CDs? Do we need to create new ones?

  • Does the hierarchy require groupers?

  • Do any concepts have strength ranges?

  • If a concept specifies more than one substance, does each substance have an associated strength?

  • See this page for discussion: Diagnostic products

  • Draft editorial guidelines: Editorial Guidelines for Diagnostic Products Used for Susceptibility Testing

6

Next meeting

@Daniel Karlsson

• Next meeting is on on 2018-08-20

• As the LOINC project is on hold, we will shift to monthly Observables calls

7

AOB

@Daniel Karlsson