Precursor B and T cell neoplasms
Please note the following are subject to change until the time of release.
Summary of changes made to B- cell precursor neoplasm and T-cell precursor neoplasm content:
Summary of content changes in HQ3-4: Precursor cells
Content changes pertain to <<418152006 |Precursor B-cell neoplasm (morphologic abnormality)| and <<415156005 |Precursor T-cell neoplasm (morphologic abnormality)|. Hierarchy and associated disorder concepts were reviewed by the Histology Quality Improvement Project Group.
Content was revised based on the Blue Book 5th edition ‘B-cell lymphoid proliferations and lymphomas:Precursor B-cell neoplasms’ and ‘T-cell and NK-cell lymphoid proliferations and lymphomas: Precursor T-cell neoplasms’ chapters and sections and SNOMED CT editorial guidelines. Below are more details about the proposed changes.
Morphologic abnormality concepts: 49
Disorder concepts: 35
Situation concepts: 1
Updates reflect revised WHO naming conventions, new morphology/disorder concepts, and updates to existing morphology/disorder concepts that reflect current medical knowledge.
List of concepts added or inactivated:
16 new concepts added:
SCTID | FSN |
1373860004 | Malignant B-lymphoblastic leukemia-lymphoma with DUX4 rearrangement (morphologic abnormality) |
1373863002 | Malignant B-lymphoblastic leukemia-lymphoma with NUTM1 rearrangement (morphologic abnormality) |
1373861000 | Malignant B-lymphoblastic leukemia-lymphoma with MEF2D rearrangement (morphologic abnormality) |
1373864008 | Malignant B-lymphoblastic leukemia-lymphoma with MYC rearrangement (morphologic abnormality) |
1373858001 | Malignant B-lymphoblastic leukemia-lymphoma with ETV6::RUNX1-like features (morphologic abnormality) |
1373862007 | Malignant B-lymphoblastic leukemia-lymphoma with ZNF384 rearrangement (morphologic abnormality) |
1373865009 | Malignant B-lymphoblastic leukemia-lymphoma with PAX5alt (morphologic abnormality) |
1373859009 | Malignant B-lymphoblastic leukemia-lymphoma with TCF3::HLF fusion (morphologic abnormality) |
1373866005 | Malignant B-lymphoblastic leukemia-lymphoma with PAX5 p.P80R (morphologic abnormality) |
1381353002 | Malignant acute leukemia with BCR::ABL1 fusion (morphologic abnormality) |
1373856002 | Malignant B-lymphoblastic leukemia-lymphoma with low hypodiploidy (morphologic abnormality) |
1373855003 | Malignant B-lymphoblastic leukemia-lymphoma with near haploid hypodiploidy (morphologic abnormality) |
1373857006 | Malignant B-lymphoblastic leukemia-lymphoma with high hypodiploidy (morphologic abnormality) |
1401851008 | Malignant acute undifferentiated leukemia (morphologic abnormality) |
1380211005 | Malignant precursor cell lymphoblastic leukemia-lymphoma (morphologic abnormality) |
1401852001 | Malignant acute lymphoblastic leukemia with BCR::ABL1 fusion (morphologic abnormality) |
14 concepts inactivated:
Id | FSN | Reason | Assoc Type | Assoc Value |
721308005 | Acute leukemia of ambiguous lineage (disorder) | DUPLICATE | SAME AS | 1187123005 |Mixed phenotype acute leukemia (disorder)| |
277573001 | Common acute lymphoblastic leukemia (disorder) | AMBIGUOUS | POSSIBLY EQUIVALENT TO | 1217301006 |Malignant precursor cell lymphoblastic leukemia-lymphoma (disorder)| |
277573001 | Common acute lymphoblastic leukemia (disorder) | AMBIGUOUS | POSSIBLY EQUIVALENT TO | 277572006 |Malignant B-lymphoblastic leukemia-lymphoma (disorder)| |
277574007 | Null cell acute lymphoblastic leukemia (disorder) | DUPLICATE | SAME AS | 1264458000 |Acute undifferentiated leukemia (disorder)| |
397345009 | Acute leukemia of ambiguous lineage (morphologic abnormality) | DUPLICATE | SAME AS | 450913003 |Malignant acute leukemia of mixed or ambiguous lineage (morphologic abnormality)| |
426955004 | Philadelphia chromosome-positive acute lymphoblastic leukemia (morphologic abnormality) | OUTDATED | REPLACED BY | 1401852001 |Malignant acute lymphoblastic leukemia with BCR::ABL1 fusion (morphologic abnormality)| |
128823009 | Precursor B-cell lymphoblastic leukemia (morphologic abnormality) | OUTDATED | REPLACED BY | 1162660006 |Malignant B lymphoblastic leukemia-lymphoma (morphologic abnormality)| |
128807009 | Precursor B-cell lymphoblastic lymphoma (morphologic abnormality) | OUTDATED | REPLACED BY | 1162660006 |Malignant B lymphoblastic leukemia-lymphoma (morphologic abnormality)| |
418152006 | Precursor B-cell neoplasm (morphologic abnormality) | OUTDATED | REPLACED BY | 1162660006 |Malignant B lymphoblastic leukemia-lymphoma (morphologic abnormality)| |
397347001 | Precursor B-lymphoblastic leukemia/lymphoblastic lymphoma (morphologic abnormality) | DUPLICATE | SAME AS | 1162660006 |Malignant B lymphoblastic leukemia-lymphoma (morphologic abnormality)| |
128822004 | Precursor cell lymphoblastic leukemia (morphologic abnormality) | OUTDATED | REPLACED BY | 1380211005 |Malignant precursor cell lymphoblastic leukemia-lymphoma (morphologic abnormality)| |
128806000 | Precursor cell lymphoblastic lymphoma (morphologic abnormality) | OUTDATED | REPLACED BY | 1380211005 |Malignant precursor cell lymphoblastic leukemia-lymphoma (morphologic abnormality)| |
128824003 | T-lymphoblastic leukemia (morphologic abnormality) | OUTDATED | REPLACED BY | 397348006 |Malignant T-lymphoblastic leukemia-lymphoma (morphologic abnormality)| |
128808004 | T-lymphoblastic lymphoma (morphologic abnormality) | OUTDATED | REPLACED BY | 397348006 |Malignant T-lymphoblastic leukemia-lymphoma (morphologic abnormality)| |